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Pasternak A
Smiles: NC(=N)NCCC(O)=O
In vitro: Cytochalasin J was identified as a deacetylated analog of cytochalasin H that weakly inhibited actin assembly but significantly altered mitotic spindle microtubule organization and kinetochore structure
3-thiazol-2-yl)benzene-1-sulfonamide
2 weeks) inhibits growth of syngeneic tumors by 80%
LY 2389575 hydrochloride 17454 Pasternak ALY2389575 is described here instead of LY2389575 hydrochloride. LY2389575 is a selective negative allosteric modulator (NAM) of metabotropic glutamate receptor 3 (mGlu3) with an IC50 value of 4. 2 M . The metabotropic glutamate receptors (mGlus) are members of the GPCR family C. They are characterized by a large extracellular amino terminal domain for binding agonist. Eight mGlus had been found and were assigned to three groups based on their
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